UniProtKB-GOA are pleased to announce the inclusion in their database of electronic GO annotations created by EnsemblPlants/Gramene.

The annotations are created using a similar concept to the Ensembl Compara pipeline that has been creating annotations for vertebrate species since 2006. Manually curated GO annotations are projected from Arabidopsis thaliana or Oryza sativa proteins onto proteins from one or more target species based on gene orthology obtained from Ensembl Compara.

Location: EBI - Hinxton, near Cambridge, UK
Staff Category: Staff Member
Contract Duration: 3 years
Grading: 5
Closing Date: 26 June 2011
Reference number: EBI_00089

*Job Description*
The Universal Protein Resource (UniProt) group at the European
Bioinformatics Institute (EBI) is seeking to recruit a Scientific
Curator for a demanding role in the curation of the UniProt databases.
The mission of the UniProt team is to provide the scientific community
with a comprehensive, high quality and freely accessible resource of
protein sequence and functional information.

The GO Consortium is currently looking at improving the terms and annotations associated with the apoptosis process. If you would like to contribute to this effort please have a look here http://wiki.geneontology.org/index.php/Apoptosis, or contact us (http://www.geneontology.org/GO.contacts.shtml).

On the 1st of June 2010, the format of GO annotation files available from
the GO Consortium web and ftp site changed, with files being supplied
in a 17-column GAF format (GAF2.0) instead of the current 15 columns.

The format of the new annotation file is described in the GO web page below:

http://www.geneontology.org/GO.format.gaf-2_0.shtml

CARDIOVASCULAR GENE ONTOLOGY ANNOTATION INITIATIVE
Providing Full Gene Ontology Annotation To Genes Associated With Cardiovascular Processes

Issue 8 - January 2010

Editor - Ruth Lovering

providing full GO annotation to genes associated with cardiovascular processes

providing full GO annotation to genes associated with cardiovascular processes

Gene annotation
We are now approaching the end of the second year of this initiative and can report that to date we have annotated 1333 proteins with over 10,000 GO terms, over half of these annotations are to human proteins.

Gene Ontology development

The Reference Genome Project of the GO Consortium aims to comprehensively annotate all the gene products from human, as well as that of eleven important model organisms: Arabidopsis thaliana, Caenorhabditis elegans, Danio rerio, Dictyostelium discoideum, Drosophila melanogaster, Escherichia coli, Gallus gallus, Mus musculus, Rattus norvegicus, Saccharomyces cerevisiae, and Schizosaccharomyces pombe. These different species are being used to model various, complementary aspects of biology.

The Renal GO Annotation Initiative aims to provide a unique public resource for the international renal research community by generating high quality, detailed functional GO annotation for mammalian gene products implicated in renal development, functional processes and disease.

For more information see our website or download the inaugural Renal GO Annotation Initiative newsletter.

The Gene Ontology Annotation (GOA) group at the European Bioinformatics Institute (EBI) has now reached over 40 million GO annotations as of the April 2009 release.

GOA provides both manual and electronic annotations to over 5 million proteins from all species in the UniProt Knowledgebase. Our annotations can be obtained from the EBI’s QuickGO browser, the EBI FTP site or from the Gene Ontology Consortium’s website.