CARDIOVASCULAR GENE ONTOLOGY ANNOTATION INITIATIVE
Providing Full Gene Ontology Annotation To Genes Associated With Cardiovascular Processes

Issue 8 - January 2010

Editor - Ruth Lovering

providing full GO annotation to genes associated with cardiovascular processes

In the latest GO Bibliography update, we have added two more publications from the GO Consortium:

Semi-automated curation of protein subcellular localization: a text mining-based approach to Gene Ontology (GO) cellular component curation.
Van Auken K, Jaffery J, Chan JN, Muller HM, Sternberg PW.
BMC Bioinformatics. 2009 Jul 21;10(1):228. [Epub ahead of print]
PMID: 19622167

Introduction to the proceedings of the Avian Genomics and Gene Ontology Annotation Workshop.

For anyone interested in plant-associated microbes, symbiosis and other multi-species interactions, or microbial annotation, participants in the PAMGO [Plant-Associated Microbe Gene Ontology] project have published a paper, "Applying the Gene Ontology in microbial annotation.". It details aspects of both the ontology development and the annotation processes necessitated by the project, as well as providing insight into the world of GO, as seen through microbial eyes.

We have added another new set of papers to the GO Bibliography. A small selection of the new publications:

Transcriptomes and pathways associated with infectivity, survival and immunogenicity in Brugia malayi L3.
Li BW, Rush AC, Mitreva M, Yin Y, Spiro D, Ghedin E, Weil GJ.
BMC Genomics. 2009 Jun 15;10(1):267. [Epub ahead of print]
PMID: 19527522

Gene Ontology Analysis of GWA Study Data Sets Provides Insights into the Biology of Bipolar Disorder.

The Reference Genome Project of the GO Consortium aims to comprehensively annotate all the gene products from human, as well as that of eleven important model organisms: Arabidopsis thaliana, Caenorhabditis elegans, Danio rerio, Dictyostelium discoideum, Drosophila melanogaster, Escherichia coli, Gallus gallus, Mus musculus, Rattus norvegicus, Saccharomyces cerevisiae, and Schizosaccharomyces pombe. These different species are being used to model various, complementary aspects of biology.

We have just added over two dozen new publications to the GO Bibliography, describing the use of GO in a wide range of transcriptomic and proteomic experiments, as well as new tools that work with GO and other ontologies.

A few highlights:

The Role of Cholesterol Pathways in Norovirus Replication.
Chang KO.
J Virol. 2009 Jun 10.
PMID: 19515767

Seeing the Forest for the Trees: Using the Gene Ontology to re-structure Hierarchical clustering.
Dotan-Cohen D, Kasif S, Melkman AA.
Bioinformatics. 2009 Jun 3.