We are pleased to announce the publication of our latest paper, a collaboration between the UCL-based Cardiovascular Gene Ontology Annotation Initiative (http://www.ucl.ac.uk/cardiovasculargeneontology/) and the UniProt-GOA Renal Gene Ontology Initiative (http://www.ebi.ac.uk/GOA/kidney/), which describes the benefit of performing focused annotation on proteins implicated in specific organ development and function. We show that such annotation efforts lead to improved interpretation of results from cardiovascular-related microarray datasets.

The latest quarterly newsletter (October 2011) produced by the Cardiovascular Gene Ontology Annotation Initiative is now available at http://www.ucl.ac.uk/cardiovasculargeneontology/Newsletters.

The Cardiovascular Gene Ontology Annotation Initiative represents a collaboration between University College London and the European Bioinformatics Institute (EBI), funded by the British Heart Foundation (grant SP/07/007/23671).

www.cardiovasculargeneontology.com
www.ebi.ac.uk/GOA/CVI

The latest quarterly newsletter (April 2011) produced by the Cardiovascular Gene Ontology Annotation Initiative is now available at http://www.ucl.ac.uk/cardiovasculargeneontology/Newsletters/Issue13.

The Cardiovascular Gene Ontology Annotation Initiative represents a collaboration between University College London and the European Bioinformatics Institute (EBI), funded by the British Heart Foundation (grant SP/07/007/23671).

The latest quarterly newsletter (January 2011) produced by the Cardiovascular Gene Ontology Annotation Initiative is now available at http://www.ucl.ac.uk/cardiovasculargeneontology/Newsletters/Issue12.

The Cardiovascular Gene Ontology Annotation Initiative represents a collaboration between University College London and the European Bioinformatics Institute (EBI), funded by the British Heart Foundation. This annotation group is a member of the GO Consortium.

The GO Consortium has an update in the 2010 NAR Database Issue:

The Gene Ontology in 2010: extensions and refinements.
The Gene Ontology Consortium.
Nucleic Acids Res. 2010 Jan;38(Database issue):D331-5. Epub 2009 Nov 17.
PMID: 19920128

The 2010 NAR Database Issue also includes articles on numerous databases that use GO in various ways.

GO Consortium members have also published a paper on using GO to study developmental biology:

Representing ontogeny through ontology: A developmental biologist's guide to the gene ontology.

GO Consortium members have recently published several papers on their applications of Gene Ontology terms and annotations in horse, chicken and mouse:

Facilitating functional annotation of chicken microarray data.
Buza TJ, Kumar R, Gresham CR, Burgess SC, McCarthy FM.
BMC Bioinformatics. 2009 Oct 8;10 Suppl 11:S2.
PMID: 19811685

Integrating phenotype and gene expression data for predicting gene function.
Malone BM, Perkins AD, Bridges SM.
BMC Bioinformatics. 2009 Oct 8;10 Suppl 11:S20.

The GO Annotation (GOA) group at EBI has published a paper on the QuickGO browser:
QuickGO: a web-based tool for Gene Ontology searching.
Binns D, Dimmer E, Huntley R, Barrell D, O'Donovan C, Apweiler R.
Bioinformatics. 2009 Sep 10. [Epub ahead of print]
PMID: 1974499

This paper has been included in the most recent GO Bibliography" update, along with a number of other interesting publications using GO, such as:

Expression profiles of early esophageal squamous cell carcinoma by cDNA microarray.

Ten review articles describing how the Gene Ontology is bringing benefits to the study of the microbial world have been published in a special issue of Trends in Microbiology, co-edited by Virginia Bioinformatics Institute professor Brett Tyler.

A paper describing the Gene Ontology Reference Genome Project (as featured in a recent special report) is now available online.

The Gene Ontology's Reference Genome Project: a unified framework for functional annotation across species.
Reference Genome Group of the Gene Ontology Consortium.
PLoS Comput Biol. 2009 Jul;5(7):e1000431. Epub 2009 Jul 3.
PMID: 19578431

Abstract: