We are pleased to announce the publication of our latest paper, a collaboration between the UCL-based Cardiovascular Gene Ontology Annotation Initiative (http://www.ucl.ac.uk/cardiovasculargeneontology/) and the UniProt-GOA Renal Gene Ontology Initiative (http://www.ebi.ac.uk/GOA/kidney/), which describes the benefit of performing focused annotation on proteins implicated in specific organ development and function. We show that such annotation efforts lead to improved interpretation of results from cardiovascular-related microarray datasets. The effort to improve the annotation of proteins involved in renal development and function is hoped to achieve a similarly successful result.
The impact of focused gene ontology curation of specific mammalian systems. Alam-Faruque Y, Huntley RP, Khodiyar VK, Camon EB, Dimmer EC, Sawford T, Martin MJ, O'Donovan C, Talmud PJ, Scambler P, Apweiler R, Lovering RC. PLoS One. 2011;6(12):e27541. Epub 2011 Dec 9. PMID: 22174742.
http://www.plosone.org/article/fetchObjectAttachment.action?uri=info%3Ad...

There is also a blog about the article at http://www.genomeweb.com/blog/week-plos-166